GNAQ 抗体 (Center)
Quick Overview for GNAQ 抗体 (Center) (ABIN2855848)
抗原
See all GNAQ 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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交叉反应
- 犬, 猪, 牛, 猕猴
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交叉反应 (详细)
- Dog (100 %), Pig (100 %), Rhesus Monkey (100 %), Bovine (100 %)
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产品特性
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Rabbit polyclonal antibody to GNAQ (guanine nucleotide binding protein (G protein), q polypeptide)
GNAQ antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human GNAQ. The exact sequence is proprietary.
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亚型
- IgG
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应用备注
- Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
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说明
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Positive Control: 3xFlag-human GNAQ-transfected 293T
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "Protein expression of KIT, BRAF, GNA11, GNAQ and RASSF1 in feline diffuse iris melanomas." in: Veterinary journal (London, England : 1997), Vol. 249, pp. 33-40, (2019) (PubMed).
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: "Protein expression of KIT, BRAF, GNA11, GNAQ and RASSF1 in feline diffuse iris melanomas." in: Veterinary journal (London, England : 1997), Vol. 249, pp. 33-40, (2019) (PubMed).
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- GNAQ (Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ))
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别名
- GNAQ
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背景
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Guanine nucleotide-binding proteins are a family of heterotrimeric proteins that couple cell surface, 7-transmembrane domain receptors to intracellular signaling pathways. Receptor activation catalyzes the exchange of GTP for GDP bound to the inactive G protein alpha subunit resulting in a conformational change and dissociation of the complex. The G protein alpha and beta-gamma subunits are capable of regulating various cellular effectors. Activation is terminated by a GTPase intrinsic to the G-alpha subunit. G-alpha-q is the alpha subunit of one of the heterotrimeric GTP-binding proteins that mediates stimulation of phospholipase C-beta (MIM 600230).[supplied by OMIM]
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分子量
- 42 kDa
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基因ID
- 2776
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途径
- JAK/STAT Signaling, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction
抗原
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