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GNAQ 抗体 (Center)

This anti-GNAQ antibody is a 兔 多克隆 antibody detecting GNAQ in WB 和 IHC (p). Suitable for 人, 小鼠 和 大鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2855848
发货至: 中国

Quick Overview for GNAQ 抗体 (Center) (ABIN2855848)

抗原

See all GNAQ 抗体
GNAQ (Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ))

适用

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  • 5
  • 5
  • 3
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  • 3
  • 3
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  • 1
人, 小鼠, 大鼠

宿主

  • 43
  • 17
  • 1

克隆类型

  • 43
  • 18
多克隆

标记

  • 30
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GNAQ antibody is un-conjugated

应用范围

  • 43
  • 21
  • 13
  • 13
  • 9
  • 6
  • 6
  • 4
  • 3
  • 2
  • 2
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 15
    • 9
    • 9
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center

    交叉反应

    犬, 猪, 牛, 猕猴

    交叉反应 (详细)

    Dog (100 %), Pig (100 %), Rhesus Monkey (100 %), Bovine (100 %)

    产品特性

    Rabbit polyclonal antibody to GNAQ (guanine nucleotide binding protein (G protein), q polypeptide)
    GNAQ antibody

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human GNAQ. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

    说明

    Positive Control: 3xFlag-human GNAQ-transfected 293T

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Rushton, Korb, Kummer, Reichart, Fuchs-Baumgartinger, Tichy, Nell: "Protein expression of KIT, BRAF, GNA11, GNAQ and RASSF1 in feline diffuse iris melanomas." in: Veterinary journal (London, England : 1997), Vol. 249, pp. 33-40, (2019) (PubMed).

  • 抗原

    GNAQ (Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ))

    别名

    GNAQ

    背景

    Guanine nucleotide-binding proteins are a family of heterotrimeric proteins that couple cell surface, 7-transmembrane domain receptors to intracellular signaling pathways. Receptor activation catalyzes the exchange of GTP for GDP bound to the inactive G protein alpha subunit resulting in a conformational change and dissociation of the complex. The G protein alpha and beta-gamma subunits are capable of regulating various cellular effectors. Activation is terminated by a GTPase intrinsic to the G-alpha subunit. G-alpha-q is the alpha subunit of one of the heterotrimeric GTP-binding proteins that mediates stimulation of phospholipase C-beta (MIM 600230).[supplied by OMIM]

    分子量

    42 kDa

    基因ID

    2776

    途径

    JAK/STAT Signaling, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction
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