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ETS2 抗体 (Center)

This anti-ETS2 antibody is a 兔 多克隆 antibody detecting ETS2 in WB, IF, IHC (p), IP, ChIP 和 ICC. Suitable for 人 和 大鼠. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN2855845
发货至: 中国

Quick Overview for ETS2 抗体 (Center) (ABIN2855845)

抗原

See all ETS2 抗体
ETS2 (V-Ets Erythroblastosis Virus E26 Oncogene Homolog 2 (ETS2))

适用

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人, 大鼠

宿主

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克隆类型

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多克隆

标记

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This ETS2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Chromatin Immunoprecipitation (ChIP), Immunocytochemistry (ICC)
  • 抗原表位

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    Center

    产品特性

    Rabbit Polyclonal antibody to ETS2 (v-ets erythroblastosis virus E26 oncogene homolog 2 (avian))
    ETS2 antibody

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human ETS2. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    Suggested dilution Reference ChIP assay Assay-dependent dilution ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Immunoprecipitation 1:100-1:500* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceChIP assayAssay-dependent dilution ICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Immunoprecipitation1:100-1:500* Western blot1:500-1:3000*

    说明

    Positive Control: HeLa

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1XPBS, 1 % BSA, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Gluck, Glathar, Tsompana, Nowak, Garrett-Sinha, Buck, Sinha: "Molecular dissection of the oncogenic role of ETS1 in the mesenchymal subtypes of head and neck squamous cell carcinoma." in: PLoS genetics, Vol. 15, Issue 7, pp. e1008250, (2019) (PubMed).

    Yuan, Jiang, Mayakonda, Huang, Ding, Lin, Yu, Lu, Loh, Chow, Savage, Tyner, Lin, Koeffler: "Super-Enhancers Promote Transcriptional Dysregulation in Nasopharyngeal Carcinoma." in: Cancer research, Vol. 77, Issue 23, pp. 6614-6626, (2018) (PubMed).

    Helbig, Wockner, Bouendeu, Hille-Betz, McCue, French, Edwards, Pickett, Reddel, Chenevix-Trench, Dörk, Beesley: "Functional dissection of breast cancer risk-associated TERT promoter variants." in: Oncotarget, Vol. 8, Issue 40, pp. 67203-67217, (2017) (PubMed).

  • 抗原

    ETS2 (V-Ets Erythroblastosis Virus E26 Oncogene Homolog 2 (ETS2))

    别名

    ETS2

    背景

    ETS transcriptions factors, such as ETS2, regulate numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis. The conserved ETS domain within these proteins is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes (Dwyer et al., 2007 [PubMed 17986575]).[supplied by OMIM]

    Cellular Localization: Nucleus

    分子量

    53 kDa

    基因ID

    2114

    途径

    EGFR Signaling Pathway, Myometrial Relaxation and Contraction
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