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GLB1 抗体

This anti-GLB1 antibody is a 兔 多克隆 antibody detecting GLB1 in WB, IF, ICC 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2855812
发货至: 中国

Quick Overview for GLB1 抗体 (ABIN2855812)

抗原

See all GLB1 抗体
GLB1 (Galactosidase, beta 1 (GLB1))

适用

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宿主

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克隆类型

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多克隆

标记

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This GLB1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 交叉反应

    人, 大鼠

    产品特性

    Rabbit polyclonal antibody to beta-Gal (galactosidase, beta 1)
    beta-Gal antibody [N2C3]

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human beta-Gal. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Validation: Orthogonal

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.35 mg/mL

    缓冲液

    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Chang, Su, Chen, Chen, Chen, Hsiao: "Secretory RAB GTPase 3C modulates IL6-STAT3 pathway to promote colon cancer metastasis and is associated with poor prognosis." in: Molecular cancer, Vol. 16, Issue 1, pp. 135, (2018) (PubMed).

  • 抗原

    GLB1 (Galactosidase, beta 1 (GLB1))

    别名

    galactosidase beta 1

    背景

    This gene encodes beta-galactosidase-1, a lysosomal enzyme that hydrolyzes the terminal beta-galactose from ganglioside substrates and other glycoconjugates. Defects in this gene are the cause of GM1-gangliosidosis and Morquio B syndrome. Multiple transcript variants encoding different isoforms have been found for this gene.

    Cellular Localization: Isoform 1: Lysosome , Isoform 2: Cytoplasm , perinuclear region

    分子量

    76 kDa

    基因ID

    2720

    UniProt

    P16278

    途径

    Glycosaminoglycan Metabolic Process
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