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IDH3A 抗体

This anti-IDH3A antibody (ABIN2855763) is a Rabbit Polyclonal antibody detecting IDH3A in WB, IF, IHC (p), ICC. Suitable for Human.
产品编号 ABIN2855763
发货至: 中国

Quick Overview for IDH3A 抗体 (ABIN2855763)

抗原

See all IDH3A 抗体
IDH3A (Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A))

适用

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宿主

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克隆类型

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多克隆

标记

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This IDH3A antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
  • 交叉反应

    人, 小鼠, 大鼠, 斑马鱼

    产品特性

    Rabbit Polyclonal antibody to IDH3A (isocitrate dehydrogenase 3 (NAD+) alpha)
    IDH3A antibody

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human IDH3A. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: Mouse brain , rat brain

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.84 mg/mL

    缓冲液

    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    IDH3A (Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A))

    别名

    isocitrate dehydrogenase 3 (NAD(+)) alpha

    背景

    Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase.

    Cellular Localization: Mitochondrion

    分子量

    40 kDa

    基因ID

    3419

    UniProt

    P50213
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