EIF4E2 抗体
Quick Overview for EIF4E2 抗体 (ABIN2855740)
抗原
See all EIF4E2 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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交叉反应
- 人, 小鼠
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产品特性
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Rabbit polyclonal antibody to EIF4EL3 (eukaryotic translation initiation factor 4E family member 2)
EIF4E2 antibody [N1C3] -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human EIF4E2. The exact sequence is proprietary.
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Validation: KO/KD
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.27 mg/mL
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缓冲液
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "Ribosome collisions trigger cis-acting feedback inhibition of translation initiation." in: eLife, Vol. 9, (2020) (PubMed).
: "The E3 ubiquitin ligase and RNA-binding protein ZNF598 orchestrates ribosome quality control of premature polyadenylated mRNAs." in: Nature communications, Vol. 8, pp. 16056, (2018) (PubMed).
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: "Ribosome collisions trigger cis-acting feedback inhibition of translation initiation." in: eLife, Vol. 9, (2020) (PubMed).
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- EIF4E2 (Eukaryotic Translation Initiation Factor 4E Family Member 2 (EIF4E2))
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别名
- eukaryotic translation initiation factor 4E family member 2
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背景
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Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.
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分子量
- 28 kDa
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基因ID
- 9470
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UniProt
- O60573
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途径
- SARS-CoV-2 Protein Interactome
抗原
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