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TPP1 抗体

This 兔 多克隆 anti-TPP1 antibody specifically detects TPP1 in WB 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN2855723
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for TPP1 抗体 (ABIN2855723)

抗原

See all TPP1 抗体
TPP1 (Tripeptidyl Peptidase I (TPP1))

适用

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宿主

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克隆类型

  • 61
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多克隆

标记

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This TPP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 交叉反应

    产品特性

    Rabbit Polyclonal antibody to TPP1 (tripeptidyl peptidase I)
    TPP1 antibody

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human TPP1. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: A431

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    TPP1 (Tripeptidyl Peptidase I (TPP1))

    别名

    tripeptidyl peptidase 1

    背景

    This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.

    Cellular Localization: Lysosome , Melanosome

    分子量

    61 kDa

    基因ID

    1200

    UniProt

    O14773

    途径

    Cell Division Cycle, ER-Nucleus Signaling
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