L3MBTL1 抗体 (Center)
(1 reference)Quick Overview for L3MBTL1 抗体 (Center) (ABIN2855703)
抗原
See all L3MBTL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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交叉反应
- 小鼠
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交叉反应 （详细）
- mouse (88 %)
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产品特性
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Rabbit polyclonal antibody to L3MBTL (l(3)mbt-like (Drosophila))
L3MBTL antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human L3MBTL. The exact sequence is proprietary.
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亚型
- IgG
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anti-L(3)mbt-Like 1 (L3MBTL1) (AA 1-772) antibody
L3MBTL1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-L(3)mbt-Like 1 (L3MBTL1) (AA 82-298) antibodyL3MBTL1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-L(3)mbt-Like 1 (L3MBTL1) (AA 513-752) antibodyL3MBTL1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-L(3)mbt-Like 1 (L3MBTL1) (AA 451-485) antibodyL3MBTL1 适用: 小鼠 WB 宿主: 兔 Polyclonal RB53645 unconjugated
anti-L(3)mbt-Like 1 (L3MBTL1) (AA 221-270) antibodyL3MBTL1 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-L(3)mbt-Like 1 (L3MBTL1) (AA 442-491) antibodyL3MBTL1 适用: 人, 小鼠, 犬, 大鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-L(3)mbt-Like 1 (L3MBTL1) (N-Term) antibodyL3MBTL1 适用: 人, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-L(3)mbt-Like 1 (L3MBTL1) (AA 144-193) antibodyL3MBTL1 适用: 人, 豚鼠, 兔, 马, Cow WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Suggested dilution Reference ICC/IF 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Western blot1:500-1:3000*
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说明
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Positive Control: HeLaS3 , human L3MBTL-transfected 293T
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "L3MBTL1 regulates ALS/FTD-associated proteotoxicity and quality control." in: Nature neuroscience, Vol. 22, Issue 6, pp. 875-886, (2019) (PubMed).
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: "L3MBTL1 regulates ALS/FTD-associated proteotoxicity and quality control." in: Nature neuroscience, Vol. 22, Issue 6, pp. 875-886, (2019) (PubMed).
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- L3MBTL1 (L(3)mbt-Like 1 (L3MBTL1))
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别名
- L3MBTL
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背景
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This gene encodes the homolog of a protein identified in Drosophila as a suppressor of malignant transformation of neuroblasts and ganglion-mother cells in the optic centers of the brain. This gene product is localized to condensed chromosomes in mitotic cells. Overexpression of this gene in a glioma cell line results in improper nuclear segregation and cytokinesis producing multinucleated cells. Alternatively spliced transcript variants encoding different isoforms have been identified.
Cellular Localization: Nucleus -
分子量
- 84 kDa
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基因ID
- 26013
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途径
- Chromatin Binding
抗原
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