Optimal conditions should be determined byt he investigator.
限制
仅限研究用
浓度
Lot specific
缓冲液
IgG fraction supplied in PBS, pH 7.5, with no preservative added.
储存液
Without preservative
注意事项
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
储存条件
-20 °C
储存方法
Aliquot and store at -20 °C.
抗原
LYN
(V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog (LYN))
别名
LYN
背景
Lyn (also known as p53/56 Lyn) is a membrane associated protein tyrosine kinase (PTK) mostly expressed in hemopoietic cells which is important in cellular signaling. It contains an SH2 and SH3 domain and has been found to be cleaved after activation of caspases in apoptosis. A member of the Src family of PTKs, there are two known isoforms for Lyn which plays an indispensable role in the Fc epsilon RI (Fcer1) and the B cell IgM receptor signaling pathway and is essential for Syk activation and Lat phosphorylation after Fcer1 aggregation and can also phosphorylate Tec on multiple residues.