CKMT1B 抗体
Quick Overview for CKMT1B 抗体 (ABIN2855669)
抗原
See all CKMT1B 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 斑马鱼
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产品特性
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Rabbit Polyclonal antibody to Creatine kinase 1B (creatine kinase, mitochondrial 1B)
Creatine kinase 1B antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human Creatine kinase MT. The exact sequence is proprietary.
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亚型
- IgG
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anti-Creatine Kinase, Mitochondrial 1B (CKMT1B) (AA 327-417) antibody
CKMT1B 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 2C8 unconjugated
anti-Creatine Kinase, Mitochondrial 1B (CKMT1B) (AA 1-85) antibodyCKMT1B 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Creatine Kinase, Mitochondrial 1B (CKMT1B) (AA 115-220) antibodyCKMT1B 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Creatine Kinase, Mitochondrial 1B (CKMT1B) (AA 327-417) antibodyCKMT1B 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2C9 unconjugated
anti-Creatine Kinase, Mitochondrial 1B (CKMT1B) (AA 327-417) antibodyCKMT1B 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Creatine Kinase, Mitochondrial 1B (CKMT1B) (AA 1-417) antibodyCKMT1B 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
anti-Creatine Kinase, Mitochondrial 1B (CKMT1B) (AA 1-417) antibodyCKMT1B 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Creatine Kinase, Mitochondrial 1B (CKMT1B) (AA 212-388) antibodyCKMT1B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: H1299 , HeLaS3
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- CKMT1B (Creatine Kinase, Mitochondrial 1B (CKMT1B))
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别名
- creatine kinase, mitochondrial 1B
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背景
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Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80 % homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins.
Cellular Localization: Mitochondrion inner membrane, Peripheral membrane protein, Intermembrane side -
分子量
- 47 kDa
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基因ID
- 1159
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UniProt
- P12532
抗原
-
