PDE8A 抗体
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北京 101111
Quick Overview for PDE8A 抗体 (ABIN2855642)
抗原
See all PDE8A 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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产品特性
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Rabbit Polyclonal antibody to PDE8A (phosphodiesterase 8A)
PDE8A antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human PDE8A. The exact sequence is proprietary.
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亚型
- IgG
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anti-phosphodiesterase 8A (PDE8A) (AA 32-121) antibody
PDE8A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1H6 unconjugated
anti-phosphodiesterase 8A (PDE8A) (AA 596-829) antibodyPDE8A 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 8A (PDE8A) (AA 681-730) antibodyPDE8A 适用: 人, 小鼠, 大鼠, 猴, 兔, Cow, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 8A (PDE8A) (AA 551-600) antibodyPDE8A 适用: 人, 大鼠, 猴, 兔, 犬, 马, Cow, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 8A (PDE8A) antibodyPDE8A 适用: 人 WB 宿主: 小鼠 Monoclonal EM-52 unconjugated
anti-phosphodiesterase 8A (PDE8A) (AA 1-120) antibodyPDE8A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 8A (PDE8A) (AA 1-829) antibodyPDE8A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-phosphodiesterase 8A (PDE8A) (C-Term) antibodyPDE8A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 8A (PDE8A) (C-Term) antibodyPDE8A 适用: 人, 小鼠, 大鼠, 兔, 犬, 马, Cow, Pig, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 8A (PDE8A) (C-Term) antibodyPDE8A 适用: 人, 小鼠, 大鼠, 兔, 犬, 马, Cow, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- PDE8A (phosphodiesterase 8A (PDE8A))
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别名
- phosphodiesterase 8A
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背景
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Phosphodiesterases (PDEs) regulate the intracellular levels of cAMP and cGMP. These cyclic nucleotides play an important role as second messengers in multiple physiologic processes, including regulation of vascular resistance, cardiac output, visceral motility, immune response, inflammation, neuroplasticity, vision, and reproduction. PDEs comprise a large superfamily of enzymes divided into 10 families. Different PDEs can be distinguished by their structure, tissue expression, localization, substrate specificity, regulation, and sensitivity to PDE inhibitors. Diversity in structure and specificity of function make PDEs promising targets for the pharmacotherapy of diseases modulated by cyclic nucleotide signaling (Hetman et al., MIM 2000). See MIM 171885.[supplied by OMIM]
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分子量
- 93 kDa
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基因ID
- 5151
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UniProt
- O60658
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途径
- cAMP Metabolic Process
抗原
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