SART1 抗体 (Internal Region)
Quick Overview for SART1 抗体 (Internal Region) (ABIN2855616)
抗原
See all SART1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Internal Region
-
产品特性
-
Rabbit Polyclonal antibody to SART1 (squamous cell carcinoma antigen recognized by T cells)
SART1 antibody [N2C1], Internal -
纯化方法
- Purified by antigen-affinity chromatography.
-
免疫原
- Recombinant protein encompassing a sequence within the center region of human SART1. The exact sequence is proprietary.
-
亚型
- IgG
-
-
anti-Squamous Cell Carcinoma Antigen Recognized By T Cells (SART1) (AA 1-255) antibody
SART1 适用: 人 WB, IP, IHC 宿主: 兔 Polyclonal unconjugated
anti-Squamous Cell Carcinoma Antigen Recognized By T Cells (SART1) (AA 1-800) antibodySART1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Squamous Cell Carcinoma Antigen Recognized By T Cells (SART1) (C-Term) antibodySART1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Squamous Cell Carcinoma Antigen Recognized By T Cells (SART1) antibodySART1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Squamous Cell Carcinoma Antigen Recognized By T Cells (SART1) (N-Term) antibodyVerified SART1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Squamous Cell Carcinoma Antigen Recognized By T Cells (SART1) (C-Term) antibodySART1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Squamous Cell Carcinoma Antigen Recognized By T Cells (SART1) antibodySART1 适用: 人, 小鼠, 大鼠 WB, IP 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:1000-1:10000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:1000-1:10000*
-
说明
-
Conjugation Note: MH
Positive Control: Jurkat , Raji , K562 , THP-1 , HL-60 , NCI-H929 , NIH-3T3 , JC , BCL-1 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.76 mg/mL
-
缓冲液
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
-
储存液
- Thimerosal (Merthiolate)
-
注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
- SART1 (Squamous Cell Carcinoma Antigen Recognized By T Cells (SART1))
-
别名
- SART1
-
背景
-
This gene encodes two proteins, the SART1(800) protein expressed in the nucleus of the majority of proliferating cells, and the SART1(259) protein expressed in the cytosol of epithelial cancers. The SART1(259) protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation, its full-length sequence is not published yet. The two encoded proteins are thought to be involved in the regulation of proliferation. Both proteins have tumor-rejection antigens. The SART1(259) protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients. This SART1(259) antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy. The SART1(259) protein is found to be essential for the recruitment of the tri-snRNP to the pre-spliceosome in the spliceosome assembly pathway.
Cellular Localization: Nucleus -
分子量
- 90 kDa
-
基因ID
- 9092
-
途径
- Ribonucleoprotein Complex Subunit Organization
抗原
-
