KLF5 抗体
Quick Overview for KLF5 抗体 (ABIN2855604)
抗原
See all KLF5 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
-
-
交叉反应
- 人, 小鼠, 大鼠
-
产品特性
-
Rabbit Polyclonal antibody to KLF5 (Kruppel-like factor 5 (intestinal))
KLF5 antibody -
纯化方法
- Purified by antigen-affinity chromatography.
-
免疫原
- Recombinant protein encompassing a sequence within the center region of human KLF5. The exact sequence is proprietary.
-
亚型
- IgG
-
-
-
-
应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
-
说明
-
Positive Control: KLF5-transfected 293T , HeLa (500 μM CoCl2 treatment for 24 hr and 10 μM MG132 treatment for 2 hr)
Validation: KO/KD, Orthogonal, Overexpression
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.8 mg/mL
-
缓冲液
- 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
-
: "Increased AT2R expression is induced by AT1R autoantibody via two axes, Klf-5/IRF-1 and circErbB4/miR-29a-5p, to promote VSMC migration." in: Cell death & disease, Vol. 11, Issue 6, pp. 432, (2020) (PubMed).
: "KLF5 promotes cervical cancer proliferation, migration and invasion in a manner partly dependent on TNFRSF11a expression." in: Scientific reports, Vol. 7, Issue 1, pp. 15683, (2019) (PubMed).
-
: "Increased AT2R expression is induced by AT1R autoantibody via two axes, Klf-5/IRF-1 and circErbB4/miR-29a-5p, to promote VSMC migration." in: Cell death & disease, Vol. 11, Issue 6, pp. 432, (2020) (PubMed).
-
- KLF5 (Kruppel-Like Factor 5 (Intestinal) (KLF5))
-
别名
- Kruppel like factor 5
-
背景
-
This gene encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. Since the protein localizes to the nucleus and binds the epidermal growth factor response element, it is thought to be a transcription factor.
Cellular Localization: Nucleus -
分子量
- 51 kDa
-
基因ID
- 688
-
UniProt
- Q13887
抗原
-