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KLF5 抗体

Cited in 2+ publications. This 兔 多克隆 anti-KLF5 antibody specifically detects KLF5 in WB, IP, ICC, IHC (p), IF 和 IHC (fro). The antibody is reactive with 人 samples.
产品编号 ABIN2855604
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for KLF5 抗体 (ABIN2855604)

抗原

See all KLF5 抗体
KLF5 (Kruppel-Like Factor 5 (Intestinal) (KLF5))

适用

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宿主

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克隆类型

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多克隆

标记

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This KLF5 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

质量等级

KO Validated
  • 交叉反应

    人, 小鼠, 大鼠

    产品特性

    Rabbit Polyclonal antibody to KLF5 (Kruppel-like factor 5 (intestinal))
    KLF5 antibody

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human KLF5. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: KLF5-transfected 293T , HeLa (500 μM CoCl2 treatment for 24 hr and 10 μM MG132 treatment for 2 hr)

    Validation: KO/KD, Orthogonal, Overexpression

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.8 mg/mL

    缓冲液

    1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Sun, Li, Wang, Yue, Bai, Bian, Hao, Sun, Zhang, Liu: "Increased AT2R expression is induced by AT1R autoantibody via two axes, Klf-5/IRF-1 and circErbB4/miR-29a-5p, to promote VSMC migration." in: Cell death & disease, Vol. 11, Issue 6, pp. 432, (2020) (PubMed).

    Ma, Chang, Zhao, Zhao, Xiong, Cao, Yuan, Zhang, Wang, Geng, Zheng, Li: "KLF5 promotes cervical cancer proliferation, migration and invasion in a manner partly dependent on TNFRSF11a expression." in: Scientific reports, Vol. 7, Issue 1, pp. 15683, (2019) (PubMed).

  • 抗原

    KLF5 (Kruppel-Like Factor 5 (Intestinal) (KLF5))

    别名

    Kruppel like factor 5

    背景

    This gene encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. Since the protein localizes to the nucleus and binds the epidermal growth factor response element, it is thought to be a transcription factor.

    Cellular Localization: Nucleus

    分子量

    51 kDa

    基因ID

    688

    UniProt

    Q13887
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