Calpain 5 抗体
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北京 101111
Quick Overview for Calpain 5 抗体 (ABIN2855597)
抗原
See all Calpain 5 (CAPN5) 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠
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产品特性
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Rabbit polyclonal antibody to Calpain-5 (calpain 5)
Calpain-5 antibody [N1C1] -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human Calpain 5. The exact sequence is proprietary.
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亚型
- IgG
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anti-Calpain 5 (CAPN5) (AA 361-640) antibody
CAPN5 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Calpain 5 (CAPN5) (AA 26-343) antibodyCAPN5 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Calpain 5 (CAPN5) (AA 297-331) antibodyCAPN5 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal RB52879 unconjugated
anti-Calpain 5 (CAPN5) antibodyCAPN5 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Calpain 5 (CAPN5) antibodyCAPN5 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Calpain 5 (CAPN5) (AA 1-640) antibodyCAPN5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Calpain 5 (CAPN5) (AA 523-622) antibodyCAPN5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3C10 unconjugated
anti-Calpain 5 (CAPN5) antibodyCAPN5 适用: 人, 小鼠, 大鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: mouse uterus , RMS-13
Validation: Orthogonal, Overexpression
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.39 mg/mL
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缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "A novel de novo CAPN5 mutation in a patient with inflammatory vitreoretinopathy, hearing loss, and developmental delay." in: Cold Spring Harbor molecular case studies, Vol. 4, Issue 3, (2019) (PubMed).
: "Calpain-5 Expression in the Retina Localizes to Photoreceptor Synapses." in: Investigative ophthalmology & visual science, Vol. 57, Issue 6, pp. 2509-21, (2016) (PubMed).
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: "A novel de novo CAPN5 mutation in a patient with inflammatory vitreoretinopathy, hearing loss, and developmental delay." in: Cold Spring Harbor molecular case studies, Vol. 4, Issue 3, (2019) (PubMed).
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- Calpain 5 (CAPN5)
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别名
- calpain 5
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背景
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Calpains are calcium-dependent cysteine proteases involved in signal transduction in a variety of cellular processes. A functional calpain protein consists of an invariant small subunit and 1 of a family of large subunits. CAPN5 is one of the large subunits. Unlike some of the calpains, CAPN5 and CAPN6 lack a calmodulin-like domain IV. Because of the significant similarity to Caenorhabditis elegans sex determination gene tra-3, CAPN5 is also called as HTRA3.
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分子量
- 73 kDa
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基因ID
- 726
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UniProt
- O15484
抗原
-
