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ARHGDIB 抗体

This anti-ARHGDIB antibody is a 兔 多克隆 antibody detecting ARHGDIB in WB. Suitable for 人.
产品编号 ABIN2855594
发货至: 中国

Quick Overview for ARHGDIB 抗体 (ABIN2855594)

抗原

See all ARHGDIB 抗体
ARHGDIB (rho GDP Dissociation Inhibitor (GDI) beta (ARHGDIB))

适用

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宿主

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克隆类型

  • 36
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多克隆

标记

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This ARHGDIB antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 交叉反应

    人, 小鼠

    产品特性

    Rabbit polyclonal antibody to Rho GDI2 (Rho GDP dissociation inhibitor (GDI) beta)
    Rho GDI2 antibody [N1C3]

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human Rho GDI2. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: 293T , A431 , H1299 , HeLaS3 , HepG2

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    ARHGDIB (rho GDP Dissociation Inhibitor (GDI) beta (ARHGDIB))

    别名

    Rho GDP dissociation inhibitor beta

    背景

    Members of the Rho (or ARH) protein family (see MIM 165390) and other Ras-related small GTP-binding proteins (see MIM 179520) are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases (summary by Scherle et al., 1993 [PubMed 8356058]).[supplied by OMIM]

    Cellular Localization: Cytoplasm

    分子量

    23 kDa

    基因ID

    397

    UniProt

    P52566

    途径

    Caspase Cascade in Apoptosis
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