NRF1 抗体
(2 references)Quick Overview for NRF1 抗体 (ABIN2855569)
抗原
See all NRF1 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
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Rabbit Polyclonal antibody to NRF1 (nuclear respiratory factor 1)
NRF1 antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human NRF1. The exact sequence is proprietary.
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亚型
- IgG
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anti-Nuclear Respiratory Factor 1 (NRF1) (AA 201-285) antibody
NRF1 适用: 人 WB, ELISA, IHC (p), RNAi 宿主: 小鼠 Monoclonal 2F9 unconjugated
anti-Nuclear Respiratory Factor 1 (NRF1) (AA 272-288), (Middle Region) antibodyNRF1 适用: 人, 小鼠, 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Respiratory Factor 1 (NRF1) (Middle Region) antibodyNRF1 适用: 人, 小鼠, 大鼠, Cow, 兔, 马, 豚鼠, 斑马鱼, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Respiratory Factor 1 (NRF1) antibodyNRF1 适用: 人 WB, IHC, IP, ChIP 宿主: 兔 Monoclonal unconjugated
anti-Nuclear Respiratory Factor 1 (NRF1) (N-Term) antibodyNRF1 适用: 人, 小鼠, 大鼠, Cow, 兔, 马, 豚鼠, 斑马鱼, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Respiratory Factor 1 (NRF1) (AA 51-180) antibodyNRF1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Respiratory Factor 1 (NRF1) (AA 360-409) antibodyNRF1 适用: 人, 大鼠, Cow, 兔, 马, 豚鼠, 斑马鱼, 犬, 猴, 小鸡, Pig, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Respiratory Factor 1 (NRF1) (Internal Region) antibodyNRF1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Respiratory Factor 1 (NRF1) (AA 1-300) antibodyNRF1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Respiratory Factor 1 (NRF1) (AA 201-285) antibodyNRF1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: 293T nuclear , A431 nuclear , HeLa nuclear , HepG2 nuclear
Validation: Orthogonal
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.32 mg/mL
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缓冲液
- 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "Acute and chronic effects of resistance training on skeletal muscle markers of mitochondrial remodeling in older adults." in: Physiological reports, Vol. 8, Issue 15, pp. e14526, (2020) (PubMed).
: "The SIAH2-NRF1 axis spatially regulates tumor microenvironment remodeling for tumor progression." in: Nature communications, Vol. 10, Issue 1, pp. 1034, (2019) (PubMed).
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: "Acute and chronic effects of resistance training on skeletal muscle markers of mitochondrial remodeling in older adults." in: Physiological reports, Vol. 8, Issue 15, pp. e14526, (2020) (PubMed).
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- NRF1 (Nuclear Respiratory Factor 1 (NRF1))
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别名
- nuclear respiratory factor 1
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背景
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This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternate transcriptional splice variants, which encode the same protein, have been characterized. Additional variants encoding different protein isoforms have been described but they have not been fully characterized. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for "nuclear factor (erythroid-derived 2)-like 1" which has an official symbol of NFE2L1.
Cellular Localization: Nucleus -
分子量
- 54 kDa
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基因ID
- 4899
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UniProt
- Q16656
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途径
- Regulation of Lipid Metabolism by PPARalpha
抗原
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