HSD3B2 抗体
(1 reference)Quick Overview for HSD3B2 抗体 (ABIN2855488)
抗原
See all HSD3B2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
交叉反应
- 人, 小鼠
-
产品特性
-
Rabbit Polyclonal antibody to HSD3B2 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2)
HSD3B2 antibody [N3C3] -
纯化方法
- Purified by antigen-affinity chromatography.
-
免疫原
- Recombinant protein encompassing a sequence within the center region of human HSD3B2. The exact sequence is proprietary.
-
亚型
- IgG
-
-
anti-Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 2 (HSD3B2) (AA 33-122) antibody
HSD3B2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E8 unconjugated
anti-Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 2 (HSD3B2) antibodyHSD3B2 适用: 人, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 2 (HSD3B2) antibodyHSD3B2 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 2 (HSD3B2) (AA 1-372) antibodyHSD3B2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 2 (HSD3B2) (AA 1-287) antibodyHSD3B2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 2 (HSD3B2) (N-Term) antibodyHSD3B2 适用: 人, 小鼠, 大鼠, Cow, 犬, 山羊, 豚鼠, 马, 绵羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 2 (HSD3B2) antibodyHSD3B2 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 2 (HSD3B2) (N-Term) antibodyHSD3B2 适用: 人, 大鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 2 (HSD3B2) (N-Term) antibodyHSD3B2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
-
说明
-
Validation: Orthogonal
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1.24 mg/mL
-
缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
-
: "Platelets induce increased estrogen production through NF-κB and TGF-β1 signaling pathways in endometriotic stromal cells." in: Scientific reports, Vol. 10, Issue 1, pp. 1281, (2020) (PubMed).
-
: "Platelets induce increased estrogen production through NF-κB and TGF-β1 signaling pathways in endometriotic stromal cells." in: Scientific reports, Vol. 10, Issue 1, pp. 1281, (2020) (PubMed).
-
- HSD3B2 (Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 2 (HSD3B2))
-
别名
- hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
-
背景
-
The protein encoded by this gene is a bifunctional enzyme that catalyzes the oxidative conversion of delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. It plays a crucial role in the biosynthesis of all classes of hormonal steroids. This gene is predominantly expressed in the adrenals and the gonads. Mutations in this gene are associated with 3-beta-hydroxysteroid dehydrogenase, type II, deficiency. Alternatively spliced transcript variants have been found for this gene.
Cellular Localization: Endoplasmic reticulum membrane , Mitochondrion membrane -
分子量
- 42 kDa
-
基因ID
- 3284
-
UniProt
- P26439
-
途径
- Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis
抗原
-
