CDC25C 抗体
Quick Overview for CDC25C 抗体 (ABIN2855486)
抗原
See all CDC25C 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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交叉反应
- 人
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产品特性
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Rabbit Polyclonal antibody to CDC25C (cell division cycle 25 homolog C (S. pombe))
CDC25C antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human CDC25C. The exact sequence is proprietary.
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亚型
- IgG
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: A431 , HeLa
Validation: KO/KD, Orthogonal
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.63 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- CDC25C (Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C))
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别名
- cell division cycle 25C
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背景
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This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.
Cellular Localization: Nucleus -
分子量
- 53 kDa
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基因ID
- 995
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UniProt
- P30307
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途径
- Cell Division Cycle, M Phase
抗原
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