IL-10RA 抗体
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北京 101111
Quick Overview for IL-10RA 抗体 (ABIN2855471)
抗原
See all IL-10RA (IL10RA) 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠
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产品特性
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Rabbit Polyclonal antibody to IL10 Receptor alpha (interleukin 10 receptor, alpha)
IL10 Receptor alpha antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human IL10 Receptor alpha. The exact sequence is proprietary.
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亚型
- IgG
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anti-Interleukin 10 Receptor, alpha (IL10RA) (AA 132-235) antibody
IL10RA 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 10 Receptor, alpha (IL10RA) (AA 22-230) antibodyIL10RA 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 10 Receptor, alpha (IL10RA) (AA 22-235) antibodyIL10RA 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 10 Receptor, alpha (IL10RA) antibodyIL10RA 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 25GB715 unconjugated
anti-Interleukin 10 Receptor, alpha (IL10RA) (pTyr496) antibodyIL10RA 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 10 Receptor, alpha (IL10RA) (C-Term) antibodyIL10RA 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 10 Receptor, alpha (IL10RA) (Ser560) antibodyIL10RA 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 10 Receptor, alpha (IL10RA) (AA 128-177) antibodyIL10RA 适用: 人, Cow, Pig, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 10 Receptor, alpha (IL10RA) (AA 147-175) antibodyIL10RA 适用: 人 WB, FACS, IF 宿主: 兔 Polyclonal RB23343 unconjugated
anti-Interleukin 10 Receptor, alpha (IL10RA) (AA 81-180) antibodyIL10RA 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Validation:Orthogonal, Overexpression
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.85 mg/mL
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缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))
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别名
- interleukin 10 receptor subunit alpha
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背景
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The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.
Cellular Localization: Membrane, Single-pass type I membrane protein -
分子量
- 63 kDa
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基因ID
- 3587
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UniProt
- Q13651
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途径
- Growth Factor Binding
抗原
-
