NFE2 抗体 (Center)
Quick Overview for NFE2 抗体 (Center) (ABIN2855460)
抗原
See all NFE2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Center
-
交叉反应
- 猴, 猪
-
交叉反应 (详细)
- Monkey (97 %), Pig (91 %)
-
产品特性
-
Rabbit Polyclonal antibody to NF-E2 (nuclear factor (erythroid-derived 2), 45 kDa)
NF-E2 antibody [N1C3] -
纯化方法
- Purified by antigen-affinity chromatography.
-
免疫原
- Recombinant protein encompassing a sequence within the center region of human NF-E2. The exact sequence is proprietary.
-
亚型
- IgG
-
-
-
-
应用备注
- Suggested dilution Reference ICC/IF 1:100-1:1000* Immunoprecipitation Assay-dependent dilution Western blot 1:500-1:3000* ChIP-sequencing Assay-dependent dilution Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* ImmunoprecipitationAssay-dependent dilution Western blot1:500-1:3000* ChIP-sequencingAssay-dependent dilution
-
说明
-
Positive Control: 293T , mouse spleen
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1.03 mg/mL
-
缓冲液
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
-
储存液
- Thimerosal (Merthiolate)
-
注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
- NFE2 (Nuclear Factor (Erythroid-Derived 2), 45kDa (NFE2))
-
别名
- NF-E2
-
背景
-
Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.
Cellular Localization: Nucleus -
分子量
- 41 kDa
-
基因ID
- 4778
抗原
-