PIGA 抗体
Quick Overview for PIGA 抗体 (ABIN2855435)
抗原
See all PIGA 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 小鼠
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产品特性
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Rabbit Polyclonal antibody to PIGA (phosphatidylinositol glycan anchor biosynthesis, class A)
PIGA antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human PIGA. The exact sequence is proprietary.
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亚型
- IgG
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应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: NIH-3T3
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.18 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 1 % BSA, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- PIGA (Phosphatidylinositol Glycan Anchor Biosynthesis, Class A (PIGA))
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别名
- phosphatidylinositol glycan anchor biosynthesis class A
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背景
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This gene encodes a protein required for synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the biosynthetic pathway of GPI anchor. The GPI anchor is a glycolipid found on many blood cells and which serves to anchor proteins to the cell surface. Paroxysmal nocturnal hemoglobinuria, an acquired hematologic disorder, has been shown to result from mutations in this gene. Alternate splice variants have been characterized.
Cellular Localization: Endoplasmic reticulum membrane, Single-pass membrane protein -
分子量
- 54 kDa
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基因ID
- 5277
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UniProt
- P37287
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途径
- Inositol Metabolic Process
抗原
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