GABBR1 抗体
Quick Overview for GABBR1 抗体 (ABIN2855413)
抗原
See all GABBR1 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
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Rabbit Polyclonal antibody to GABA B Receptor 1 (gamma-aminobutyric acid (GABA) B receptor, 1)
GABA B Receptor 1 antibody [N2C1], Internal -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human GABA B Receptor 1. The exact sequence is proprietary.
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亚型
- IgG
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anti-gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1) (AA 52-151) antibody
GABBR1 适用: 人 WB, ELISA, IF, RNAi 宿主: 小鼠 Monoclonal 2D7 unconjugated
anti-gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1) (C-Term) antibodyGABBR1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1) (AA 873-977) antibodyGABBR1 适用: 大鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal S93A-49 unconjugated
anti-gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1) (AA 873-977) antibody (HRP)GABBR1 适用: 大鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal S93A-49 HRP
anti-gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1) (AA 873-977) antibody (FITC)GABBR1 适用: 大鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal S93A-49 FITC
anti-gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1) (AA 873-977) antibody (Biotin)GABBR1 适用: 大鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal S93A-49 Biotin
anti-gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1) (AA 873-977) antibody (PE)GABBR1 适用: 大鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal S93A-49 PE
anti-gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1) (AA 873-977) antibody (PerCP)GABBR1 适用: 大鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal S93A-49 PerCP
anti-gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1) (AA 873-977) antibody (APC)GABBR1 适用: 大鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal S93A-49 APC
anti-gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1) (AA 873-977) antibody (Atto 488)GABBR1 适用: 大鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal S93A-49 Atto 488
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: PC-3 , U87-MG , SK-N-SH , C8D30
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.43 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- GABBR1 (gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))
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别名
- gamma-aminobutyric acid type B receptor subunit 1
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背景
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Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic [GABA(A/C)] receptors, to produce fast synaptic inhibition, and metabotropic [GABA(B)] receptors, to produce slow, prolonged inhibitory signals. The GABA(B) receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA(B) receptor 1 and GABA(B) receptor 2. The GABA(B) receptor 1 gene is mapped to chromosome 6p21.3 within the HLA class I region close to the HLA-F gene. Susceptibility loci for multiple sclerosis, epilepsy, and schizophrenia have also been mapped in this region. Alternative splicing of this gene generates 4 transcript variants.
Cellular Localization: Cell membrane, Multi-pass membrane protein , Cell junction , synapse , postsynaptic cell membrane, Multi-pass membrane protein , Isoform 1E: Secreted -
分子量
- 108 kDa
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基因ID
- 2550
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UniProt
- Q9UBS5
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途径
- Positive Regulation of Peptide Hormone Secretion, cAMP Metabolic Process
抗原
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