ADRBK2 抗体 (N-Term)
Quick Overview for ADRBK2 抗体 (N-Term) (ABIN2855408)
抗原
See all ADRBK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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交叉反应
- 小鼠, 大鼠, 斑马鱼, 牛
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交叉反应 (详细)
- Mouse (92 %), Rat (92 %), Zebrafish (84 %), Bovine (95 %)
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产品特性
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Rabbit Polyclonal antibody to GRK3 (adrenergic, beta, receptor kinase 2)
GRK3 antibody [N1N2], N-term -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the N-terminus region of human GRK3. The exact sequence is proprietary.
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亚型
- IgG
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应用备注
- Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
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说明
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Positive Control: HeLa , Molt-4
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.63 mg/mL
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缓冲液
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- ADRBK2 (Adrenergic, Beta, Receptor Kinase 2 (ADRBK2))
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别名
- GRK3
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背景
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The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2 has 85 % amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95 % similarity. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function.
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分子量
- 80 kDa
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基因ID
- 157
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Thromboxane A2 Receptor Signaling
抗原
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