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ING3 抗体

This anti-ING3 antibody is a 兔 多克隆 antibody detecting ING3 in WB. Suitable for 人.
产品编号 ABIN2855406
发货至: 中国

Quick Overview for ING3 抗体 (ABIN2855406)

抗原

See all ING3 抗体
ING3 (Inhibitor of Growth Family, Member 3 (ING3))

适用

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宿主

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克隆类型

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多克隆

标记

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This ING3 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 交叉反应

    产品特性

    Rabbit polyclonal antibody to ING3 (inhibitor of growth family, member 3)
    ING3 antibody [N2N3]

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human ING3. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: H1299

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1XPBS ( pH 7), 40 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    ING3 (Inhibitor of Growth Family, Member 3 (ING3))

    别名

    inhibitor of growth family member 3

    背景

    The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed.

    Cellular Localization: Nucleus

    分子量

    47 kDa

    基因ID

    54556

    UniProt

    Q9NXR8
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