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BAG3 抗体 (C-Term)

This anti-BAG3 antibody is a 兔 多克隆 antibody detecting BAG3 in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN2855382
发货至: 中国

Quick Overview for BAG3 抗体 (C-Term) (ABIN2855382)

抗原

See all BAG3 抗体
BAG3 (BCL2-Associated Athanogene 3 (BAG3))

适用

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宿主

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克隆类型

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多克隆

标记

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This BAG3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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    C-Term

    交叉反应

    人, 小鼠

    产品特性

    Rabbit Polyclonal antibody to BAG3 (BCL2-associated athanogene 3)
    BAG3 antibody

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the C-terminus region of human BAG3. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: mouse heart

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.41 mg/mL

    缓冲液

    1XPBS ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    BAG3 (BCL2-Associated Athanogene 3 (BAG3))

    别名

    BCL2 associated athanogene 3

    背景

    BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.

    分子量

    62 kDa

    基因ID

    9531

    UniProt

    O95817
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