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EEF1A2 抗体

This anti-EEF1A2 antibody is a 兔 多克隆 antibody detecting EEF1A2 in WB 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2855358
发货至: 中国

Quick Overview for EEF1A2 抗体 (ABIN2855358)

抗原

See all EEF1A2 抗体
EEF1A2 (Eukaryotic Translation Elongation Factor 1 alpha 2 (EEF1A2))

适用

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宿主

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克隆类型

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多克隆

标记

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This EEF1A2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

KO Validated
  • 特异性

    Based on a BLAST result, it may also cross with human EEF1A1.

    交叉反应

    人, 小鼠, 大鼠, 斑马鱼

    产品特性

    Rabbit Polyclonal antibody to EEF1A2 (eukaryotic translation elongation factor 1 alpha 2)
    EEF1A2 antibody

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human EEF1A2. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: Mouse brain , mouse muscle , rat brain , 293T

    Validation: KO/KD

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.21 mg/mL

    缓冲液

    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Losada, Muñoz-Alonso, García, Sánchez-Murcia, Martínez-Leal, Domínguez, Lillo, Gago, Galmarini: "Translation Elongation Factor eEF1A2 is a Novel Anticancer Target for the Marine Natural Product Plitidepsin." in: Scientific reports, Vol. 6, pp. 35100, (2018) (PubMed).

  • 抗原

    EEF1A2 (Eukaryotic Translation Elongation Factor 1 alpha 2 (EEF1A2))

    别名

    eukaryotic translation elongation factor 1 alpha 2

    背景

    This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 2) is expressed in brain, heart and skeletal muscle, and the other isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas. This gene may be critical in the development of ovarian cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    Cellular Localization: Nucleus

    分子量

    50 kDa

    基因ID

    1917

    UniProt

    Q05639
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