HYOU1 抗体 (C-Term)
Quick Overview for HYOU1 抗体 (C-Term) (ABIN2855339)
抗原
See all HYOU1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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交叉反应
- 人, 小鼠, 植物, 大鼠
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产品特性
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Rabbit Polyclonal antibody to ORP150 (hypoxia up-regulated 1)
ORP150 antibody [C2C3], C-term -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the C-terminus region of human ORP150. The exact sequence is proprietary.
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亚型
- IgG
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anti-Hypoxia Up Regulated 1 (HYOU1) (AA 901-999) antibody
HYOU1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 6F7 unconjugated
anti-Hypoxia Up Regulated 1 (HYOU1) (AA 401-500) antibodyHYOU1 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Hypoxia Up Regulated 1 (HYOU1) (AA 695-994) antibodyHYOU1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Hypoxia Up Regulated 1 (HYOU1) antibodyHYOU1 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 6E3-2C3 unconjugated
anti-Hypoxia Up Regulated 1 (HYOU1) antibody (HRP)HYOU1 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 6E3-2C3 HRP
anti-Hypoxia Up Regulated 1 (HYOU1) antibody (FITC)HYOU1 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 6E3-2C3 FITC
anti-Hypoxia Up Regulated 1 (HYOU1) antibody (Biotin)HYOU1 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 6E3-2C3 Biotin
anti-Hypoxia Up Regulated 1 (HYOU1) antibody (PE)HYOU1 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 6E3-2C3 PE
anti-Hypoxia Up Regulated 1 (HYOU1) antibody (APC)HYOU1 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 6E3-2C3 APC
anti-Hypoxia Up Regulated 1 (HYOU1) antibody (PerCP)HYOU1 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 6E3-2C3 PerCP
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: mouse liver , rat brain , MCF-7 , MDA-MB-231
Validation: Orthogonal
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.41 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- HYOU1 (Hypoxia Up Regulated 1 (HYOU1))
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别名
- hypoxia up-regulated 1
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背景
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The protein encoded by this gene belongs to the heat shock protein 70 family. This gene uses alternative transcription start sites. A cis-acting segment found in the 5' UTR is involved in stress-dependent induction, resulting in the accumulation of this protein in the endoplasmic reticulum (ER) under hypoxic conditions. The protein encoded by this gene is thought to play an important role in protein folding and secretion in the ER. Since suppression of the protein is associated with accelerated apoptosis, it is also suggested to have an important cytoprotective role in hypoxia-induced cellular perturbation. This protein has been shown to be up-regulated in tumors, especially in breast tumors, and thus it is associated with tumor invasiveness. This gene also has an alternative translation initiation site, resulting in a protein that lacks the N-terminal signal peptide. This signal peptide-lacking protein, which is only 3 amino acids shorter than the mature protein in the ER, is thought to have a housekeeping function in the cytosol. In rat, this protein localizes to both the ER by a carboxy-terminal peptide sequence and to mitochondria by an amino-terminal targeting signal.
Cellular Localization: Endoplasmic reticulum lumen -
分子量
- 111 kDa
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基因ID
- 10525
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UniProt
- Q9Y4L1
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途径
- ER-Nucleus Signaling, SARS-CoV-2 Protein Interactome
抗原
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