TLN1 抗体 (C-Term)
Quick Overview for TLN1 抗体 (C-Term) (ABIN2855327)
抗原
See all TLN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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交叉反应
- 人, 小鼠
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产品特性
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Rabbit Polyclonal antibody to Talin-1 (talin 1)
Talin-1 antibody [C3], C-term -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the C-terminus region of human Talin-1. The exact sequence is proprietary.
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亚型
- IgG
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应用备注
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: Neuro2A , C8D30 , NIH-3T3 , Raw264.7 , C2C12
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 2.09 mg/mL
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缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- TLN1 (Talin 1 (TLN1))
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别名
- talin 1
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背景
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This gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin.
Cellular Localization: Cell projection , ruffle membrane, Peripheral membrane protein, Cytoplasmic side (By similarity) , Cytoplasm , cytoskeleton (By similarity) -
分子量
- 270 kDa
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基因ID
- 7094
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UniProt
- Q9Y490
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途径
- Cell-Cell Junction Organization, ER-Nucleus Signaling, Maintenance of Protein Location
抗原
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