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TLN1 抗体 (C-Term)

This anti-TLN1 antibody is a 兔 多克隆 antibody detecting TLN1 in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN2855327
发货至: 中国

Quick Overview for TLN1 抗体 (C-Term) (ABIN2855327)

抗原

See all TLN1 抗体
TLN1 (Talin 1 (TLN1))

适用

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宿主

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克隆类型

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多克隆

标记

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This TLN1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    C-Term

    交叉反应

    人, 小鼠

    产品特性

    Rabbit Polyclonal antibody to Talin-1 (talin 1)
    Talin-1 antibody [C3], C-term

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the C-terminus region of human Talin-1. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: Neuro2A , C8D30 , NIH-3T3 , Raw264.7 , C2C12

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    2.09 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    TLN1 (Talin 1 (TLN1))

    别名

    talin 1

    背景

    This gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin.

    Cellular Localization: Cell projection , ruffle membrane, Peripheral membrane protein, Cytoplasmic side (By similarity) , Cytoplasm , cytoskeleton (By similarity)

    分子量

    270 kDa

    基因ID

    7094

    UniProt

    Q9Y490

    途径

    Cell-Cell Junction Organization, ER-Nucleus Signaling, Maintenance of Protein Location
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