Cofilin 抗体
Quick Overview for Cofilin 抗体 (ABIN2855302)
抗原
See all Cofilin (CFL1) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
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Rabbit Polyclonal antibody to Cofilin 1 (cofilin 1 (non-muscle))
Cofilin 1 antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human Cofilin 1. The exact sequence is proprietary.
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亚型
- IgG
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: 293T
Validation: KO/KD, Orthogonal
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "Parkin Coordinates Platelet Stress Response in Diabetes Mellitus: A Big Role in a Small Cell." in: International journal of molecular sciences, Vol. 21, Issue 16, (2020) (PubMed).
: "Exosomal 2',3'-CNP from mesenchymal stem cells promotes hippocampus CA1 neurogenesis/neuritogenesis and contributes to rescue of cognition/learning deficiencies of damaged brain." in: Stem cells translational medicine, Vol. 9, Issue 4, pp. 499-517, (2020) (PubMed).
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: "Parkin Coordinates Platelet Stress Response in Diabetes Mellitus: A Big Role in a Small Cell." in: International journal of molecular sciences, Vol. 21, Issue 16, (2020) (PubMed).
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- Cofilin (CFL1) (Cofilin 1 (CFL1))
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别名
- cofilin 1
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背景
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Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH -dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM]
Cellular Localization: Nucleus matrix , Cytoplasm , cytoskeleton -
分子量
- 19 kDa
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基因ID
- 1072
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UniProt
- P23528
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途径
- Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus, CXCR4-mediated Signaling Events
抗原
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