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Prohibitin 2 抗体

This anti-Prohibitin 2 antibody is a 兔 多克隆 antibody detecting Prohibitin 2 in WB, IHC (p), IF 和 ICC. Suitable for 人.
产品编号 ABIN2855290
发货至: 中国

Quick Overview for Prohibitin 2 抗体 (ABIN2855290)

抗原

See all Prohibitin 2 (PHB2) 抗体
Prohibitin 2 (PHB2)

适用

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宿主

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克隆类型

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多克隆

标记

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This Prohibitin 2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 交叉反应

    人, 小鼠, 大鼠

    产品特性

    Rabbit Polyclonal antibody to Prohibitin 2 (prohibitin 2)
    Prohibitin 2 antibody

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human Prohibitin 2. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: Mouse brain , H1299 , HeLa

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.66 mg/mL

    缓冲液

    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    Prohibitin 2 (PHB2)

    别名

    prohibitin 2

    背景

    Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.

    Cellular Localization: Mitochondrion inner membrane (By similarity) , Cytoplasm (By similarity) , Nucleus (By similarity)

    分子量

    33 kDa

    基因ID

    11331

    UniProt

    Q99623

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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