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TALDO1 抗体 (N-Term)

This anti-TALDO1 antibody is a 兔 多克隆 antibody detecting TALDO1 in WB 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2855282
发货至: 中国

Quick Overview for TALDO1 抗体 (N-Term) (ABIN2855282)

抗原

See all TALDO1 抗体
TALDO1 (Transaldolase 1 (TALDO1))

适用

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宿主

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克隆类型

  • 59
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多克隆

标记

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This TALDO1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 15
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    N-Term

    交叉反应

    人, 小鼠

    产品特性

    Rabbit Polyclonal antibody to Transaldolase (transaldolase 1)
    Transaldolase antibody

    纯化方法

    Affinity purified by Protein A.

    免疫原

    Recombinant protein encompassing a sequence within the N-terminus region of human Transaldolase. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: A431 , Mouse brain

    Validation: Orthogonal

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    6.48 mg/mL

    缓冲液

    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Ding, Gong, Huang, Chen, Sui, Lin, Liang, Yuan, Xiang, Chen, Yin, Alexander, Wang, Song, Li, Wood, Wang: "Synthetic lethality between HER2 and transaldolase in intrinsically resistant HER2-positive breast cancers." in: Nature communications, Vol. 9, Issue 1, pp. 4274, (2018) (PubMed).

  • 抗原

    TALDO1 (Transaldolase 1 (TALDO1))

    别名

    transaldolase 1

    背景

    Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations. The second and third exon of this gene were developed by insertion of a retrotransposable element. This gene is thought to be involved in multiple sclerosis.

    Cellular Localization: Cytoplasm

    分子量

    38 kDa

    基因ID

    6888

    UniProt

    P37837
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