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MFN2 抗体 (N-Term)

This anti-MFN2 antibody is a 兔 多克隆 antibody detecting MFN2 in WB 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2855272
发货至: 中国

Quick Overview for MFN2 抗体 (N-Term) (ABIN2855272)

抗原

See all MFN2 抗体
MFN2 (Mitofusin 2 (MFN2))

适用

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宿主

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克隆类型

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多克隆

标记

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This MFN2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    N-Term

    交叉反应

    人, 小鼠

    产品特性

    Rabbit Polyclonal antibody to MFN2 (mitofusin 2)
    MFN2 antibody [N1N2], N-term

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the N-terminus region of human MFN2. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: MFN2-transfected 293T

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Li, Chen, Sun, Pang: "Enhancement of Mitochondrial Transfer by Antioxidants in Human Mesenchymal Stem Cells." in: Oxidative medicine and cellular longevity, Vol. 2017, pp. 8510805, (2018) (PubMed).

  • 抗原

    MFN2 (Mitofusin 2 (MFN2))

    别名

    mitofusin 2

    背景

    This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified.

    分子量

    86 kDa

    基因ID

    9927

    UniProt

    O95140

    途径

    Skeletal Muscle Fiber Development
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