EIF3I 抗体
Quick Overview for EIF3I 抗体 (ABIN2855240)
抗原
See all EIF3I 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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产品特性
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Rabbit Polyclonal antibody to EIF3 beta (eukaryotic translation initiation factor 3, subunit I)
EIF3 beta antibody [N2C3] -
纯化方法
- Affinity purified by Protein A.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human EIF3 beta. The exact sequence is proprietary.
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亚型
- IgG
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: A431 , H1299
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 2 mg/mL
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缓冲液
- 1XPBS ( pH 7), 40 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- EIF3I (Eukaryotic Translation Initiation Factor 3, Subunit I (EIF3I))
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别名
- eukaryotic translation initiation factor 3 subunit I
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背景
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Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
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分子量
- 37 kDa
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基因ID
- 8668
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UniProt
- Q13347
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途径
- Mitotic G1-G1/S Phases, DNA Replication, Ribonucleoprotein Complex Subunit Organization, Synthesis of DNA
抗原
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