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ACTC1 抗体

This anti-ACTC1 antibody is a 兔 多克隆 antibody detecting ACTC1 in WB, ICC, IHC (p) 和 IF. Suitable for 人. This Primary Antibody has been cited in 4+ publications.
产品编号 ABIN2855212
发货至: 中国

Quick Overview for ACTC1 抗体 (ABIN2855212)

抗原

See all ACTC1 抗体
ACTC1 (Actin, Alpha, Cardiac Muscle 1 (ACTC1))

适用

  • 42
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  • 9
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宿主

  • 27
  • 16
  • 3

克隆类型

  • 29
  • 17
多克隆

标记

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  • 1
  • 1
  • 1
  • 1
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This ACTC1 antibody is un-conjugated

应用范围

  • 38
  • 27
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Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
  • 交叉反应

    人, 小鼠, 大鼠

    产品特性

    Rabbit Polyclonal antibody to alpha Cardiac Muscle Actin (actin, alpha, cardiac muscle 1)
    alpha Cardiac Muscle Actin antibody

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human alpha Cardiac Muscle Actin. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: PC-12 , Rat2 , Jurkat , Raji , K562 , THP-1 , NIH-3T3 , JC , BCL-1 , Rat muscle

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.56 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Henry, Szabó, Sutus, Pirity: "RYBP is important for cardiac progenitor cell development and sarcomere formation." in: PLoS ONE, Vol. 15, Issue 7, pp. e0235922, (2020) (PubMed).

    Oldershaw, Owens, Sutherland, Linney, Liddle, Magana, Lash, Gill, Richardson, Meeson: "Human Cardiac-Mesenchymal Stem Cell-Like Cells, a Novel Cell Population with Therapeutic Potential." in: Stem cells and development, Vol. 28, Issue 9, pp. 593-607, (2020) (PubMed).

    Miksiunas, Rucinskas, Janusauskas, Labeit, Bironaite: "Histone Deacetylase Inhibitor Suberoylanilide Hydroxamic Acid Improves Energetic Status and Cardiomyogenic Differentiation of Human Dilated Myocardium-Derived Primary Mesenchymal Cells." in: International journal of molecular sciences, Vol. 21, Issue 14, (2020) (PubMed).

    Robertson, Wen, Yin, Chen, Smith, Paine: "Multiple Calcium Export Exchangers and Pumps Are a Prominent Feature of Enamel Organ Cells." in: Frontiers in physiology, Vol. 8, pp. 336, (2017) (PubMed).

  • 抗原

    ACTC1 (Actin, Alpha, Cardiac Muscle 1 (ACTC1))

    别名

    actin alpha cardiac muscle 1

    背景

    Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC).

    Cellular Localization: Cytoplasm , cytoskeleton

    分子量

    42 kDa

    基因ID

    70

    UniProt

    P68032

    途径

    Myometrial Relaxation and Contraction
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