GP120 抗体
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北京 101111
Quick Overview for GP120 抗体 (ABIN285511)
抗原
See all GP120 (HIV-1 gp120) 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- purified
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纯度
- > 95 % pure
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免疫原
- HIV1 gp120 antibody was raised in goat using purified native gp120 from strain IIIB as the immunogen.
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应用备注
- Optimal conditions should be determined byt he investigator.
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限制
- 仅限研究用
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浓度
- Lot specific
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缓冲液
- Protein A purified IgG fraction in 10 mM PBS, pH 7.2 with 0.1 % NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
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: "HIV-1 adaptation studies reveal a novel Env-mediated homeostasis mechanism for evading lethal hypermutation by APOBEC3G." in: PLoS pathogens, Vol. 14, Issue 4, pp. e1007010, (2018) (PubMed).
: "SERINC3 and SERINC5 restrict HIV-1 infectivity and are counteracted by Nef." in: Nature, Vol. 526, Issue 7572, pp. 218-23, (2016) (PubMed).
: "Intercellular adhesion molecule 1 promotes HIV-1 attachment but not fusion to target cells." in: PLoS ONE, Vol. 7, Issue 9, pp. e44827, (2013) (PubMed).
: "The membrane-spanning domain of gp41 plays a critical role in intracellular trafficking of the HIV envelope protein." in: Retrovirology, Vol. 7, pp. 95, (2010) (PubMed).
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- GP120 (HIV-1 gp120) (Human Immunodeficiency Virus 1 Surface Glycoprotein (HIV-1 gp120))
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别名
- HIV1 Gp120
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物质类
- Viral Protein
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背景
- Envelope glycoprotein GP120 (or gp120) is a glycoprotein exposed on the surface of the HIV envelope. The 120 in its name comes from its molecular weight of 120 kilodaltons. gp120 is essential for virus entry into cells as it plays a vital role in seeking out specific cell surface receptors for entry.
抗原
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