ADAR 抗体
Quick Overview for ADAR 抗体 (ABIN2855100)
抗原
See all ADAR 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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交叉反应
- 人, 大鼠
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产品特性
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Rabbit Polyclonal antibody to ADAR1 (adenosine deaminase, RNA-specific)
ADAR1 antibody [N3C1], Internal -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human ADAR1. The exact sequence is proprietary.
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亚型
- IgG
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: 293T , A431 , HeLa , HepG2
Validation: KO/KD
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.82 mg/mL
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缓冲液
- 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "Global analysis by LC-MS/MS of N6-methyladenosine and inosine in mRNA reveal complex incidence." in: RNA (New York, N.Y.), Vol. 31, Issue 4, pp. 514-528, (2025) (PubMed).
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: "Global analysis by LC-MS/MS of N6-methyladenosine and inosine in mRNA reveal complex incidence." in: RNA (New York, N.Y.), Vol. 31, Issue 4, pp. 514-528, (2025) (PubMed).
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- ADAR (Adenosine Deaminase, RNA-Specific (ADAR))
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别名
- adenosine deaminase RNA specific
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背景
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This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Cellular Localization: Cytoplasm , Nucleus , nucleolus -
分子量
- 136 kDa
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基因ID
- 103
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UniProt
- P55265
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途径
- Protein targeting to Nucleus
抗原
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