alpha Adducin 抗体
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北京 101111
Quick Overview for alpha Adducin 抗体 (ABIN2855099)
抗原
See all alpha Adducin (ADD1) 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 斑马鱼
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产品特性
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Rabbit Polyclonal antibody to alpha Adducin (adducin 1 (alpha))
alpha Adducin antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human alpha Adducin. The exact sequence is proprietary.
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亚型
- IgG
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anti-Adducin 1 (Alpha) (ADD1) (AA 388-560) antibody
ADD1 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Adducin 1 (Alpha) (ADD1) (pSer726) antibodyADD1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Adducin 1 (Alpha) (ADD1) antibodyADD1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Adducin 1 (Alpha) (ADD1) antibodyKD Validated ADD1 适用: 人 WB, IF (p), FACS 宿主: 小鼠 Polyclonal unconjugated
anti-Adducin 1 (Alpha) (ADD1) (AA 1-193) antibodyADD1 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 5D4H1 unconjugated
anti-Adducin 1 (Alpha) (ADD1) (AA 1-662) antibodyADD1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2C9 unconjugated
anti-Adducin 1 (Alpha) (ADD1) antibodyADD1 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Adducin 1 (Alpha) (ADD1) (Ser726) antibodyADD1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Adducin 1 (Alpha) (ADD1) (pSer726) antibodyADD1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Adducin 1 (Alpha) (ADD1) (Ser713), (Ser726) antibodyADD1 适用: 人 WB, IHC, ELISA, IF, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: Jurkat
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.02 mg/mL
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缓冲液
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- alpha Adducin (ADD1) (Adducin 1 (Alpha) (ADD1))
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别名
- adducin 1
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背景
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Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms, however, not all variants have been fully described.
Cellular Localization: Cytoplasm , cytoskeleton , Cell membrane -
分子量
- 81 kDa
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基因ID
- 118
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UniProt
- P35611
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途径
- Negative Regulation of Hormone Secretion, Regulation of Actin Filament Polymerization, Regulation of Lipid Metabolism by PPARalpha, ER-Nucleus Signaling
抗原
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