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ADAM15 抗体 (N-Term)

This 兔 多克隆 anti-ADAM15 antibody specifically detects ADAM15 in WB 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN2855098
发货至: 中国
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Quick Overview for ADAM15 抗体 (N-Term) (ABIN2855098)

抗原

See all ADAM15 抗体
ADAM15 (ADAM Metallopeptidase Domain 15 (ADAM15))

适用

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宿主

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克隆类型

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多克隆

标记

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This ADAM15 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    N-Term

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Rabbit Polyclonal antibody to ADAM15 (ADAM metallopeptidase domain 15)
    ADAM15 antibody [N1N2], N-term

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the N-terminus region of human ADAM15. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: HepG2 , NIH-3T3

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.347 mg/mL

    缓冲液

    1XPBS ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    ADAM15 (ADAM Metallopeptidase Domain 15 (ADAM15))

    别名

    ADAM metallopeptidase domain 15

    背景

    The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.

    Cellular Localization: Membrane

    分子量

    93 kDa

    基因ID

    8751

    UniProt

    Q13444
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