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ITGAL 抗体 (Center)

This anti-ITGAL antibody is a 兔 多克隆 antibody detecting ITGAL in WB. Suitable for 人.
产品编号 ABIN2855092
发货至: 中国

Quick Overview for ITGAL 抗体 (Center) (ABIN2855092)

抗原

See all ITGAL 抗体
ITGAL (Integrin alpha-L (ITGAL))

适用

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宿主

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克隆类型

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多克隆

标记

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This ITGAL antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Center

    交叉反应

    Chimpanzee

    交叉反应 (详细)

    Chimpanzee (100 %)

    产品特性

    Rabbit polyclonal antibody to CD11a (integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide))
    CD11a antibody [N2N3]

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human CD11a. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*

    说明

    Positive Control: THP-1

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    ITGAL (Integrin alpha-L (ITGAL))

    别名

    CD11a

    背景

    ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene.

    Cellular Localization: Membrane, Single-pass type I membrane protein

    分子量

    129 kDa

    基因ID

    3683

    途径

    Activated T Cell Proliferation, Integrin Complex
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