ITGAL 抗体 (Center)
Quick Overview for ITGAL 抗体 (Center) (ABIN2855092)
抗原
See all ITGAL 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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交叉反应
- Chimpanzee
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交叉反应 (详细)
- Chimpanzee (100 %)
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产品特性
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Rabbit polyclonal antibody to CD11a (integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide))
CD11a antibody [N2N3] -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human CD11a. The exact sequence is proprietary.
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亚型
- IgG
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应用备注
- Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*
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说明
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Positive Control: THP-1
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- ITGAL (Integrin alpha-L (ITGAL))
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别名
- CD11a
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背景
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ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene.
Cellular Localization: Membrane, Single-pass type I membrane protein -
分子量
- 129 kDa
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基因ID
- 3683
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途径
- Activated T Cell Proliferation, Integrin Complex
抗原
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