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SOX2 抗体

Name: SOX2 抗体
Brand: antibodies-online
SKU: ABIN2855073
Availability: OutOfStock

This anti-SOX2 antibody is a 兔多克隆 antibody detecting SOX2 in WB, IF, FACS, ICC 和 IHC (fro). Suitable for 人. This Primary Antibody has been cited in 3+ publications.

WB Image Sample (30 ug of whole cell lysate) A: GL261 10% SDS PAGE antibody diluted at 1:1000 (SOX2 抗体)

FACS

ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed Human ESC, using SOX2, antibody at 1:100 dilution. (SOX2 抗体)

ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed A549, using SOX2, antibody at 1:200 dilution. (SOX2 抗体)

IHC-Fr Image Sox2 antibodies detects Sox2 proteins on embryonic mouse brain by immunohistochemical analysis. (SOX2 抗体)

IHC

ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed human embryonic stem cell, using SOX2, antibody at 1:100 dilution. (SOX2 抗体)

WB Image Sample (20 ug of whole cell lysate) A: A431 , 10% SDS PAGE antibody diluted at 1:1000 (SOX2 抗体)

IHC

WB Image Sample (20 ug of whole cell lysate) A: Human ESC 10% SDS PAGE antibody diluted at 1:1000 (SOX2 抗体)

ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed mouse ESC, using SOX2, antibody at 1:200 dilution. (SOX2 抗体)

SOX2 mediates growth of bladder cancer cells. (SOX2 抗体)

12 images

(3 references)

产品编号 ABIN2855073

发货至: 中国

Quick Overview for SOX2 抗体 (ABIN2855073)

抗原

See all SOX2 抗体

SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

适用

人

宿主

兔

克隆类型

多克隆

标记

This SOX2 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

质量等级

KO Validated

Discover our top product SOX2 Primary Antibody

交叉反应

人, 小鼠

产品特性

Rabbit Polyclonal antibody to SOX2 (SRY (sex determining region Y)-box 2)
SOX2 antibody

纯化方法

Purified by antigen-affinity chromatography.

免疫原

Recombinant protein encompassing a sequence within the center region of human SOX2. The exact sequence is proprietary.

亚型

IgG
anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) antibody
KO Validated SOX2 适用: 人 WB, IF, FACS, ICC, IHC (p), IP, IHC (fro), CUT&RUN 宿主: 兔 Polyclonal unconjugated

anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 227-317) antibody
SOX2 适用: 人, 小鼠, 大鼠, 山羊 WB, ELISA, FACS, ICC, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 1-140) antibody
SOX2 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 1-317) antibody
SOX2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 176-305) antibody
SOX2 适用: 人, 小鼠 WB, ELISA, IHC, Coat, StM 宿主: 小鼠 Monoclonal SOX2-1791 unconjugated

anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (N-Term) antibody
SOX2 适用: 人, 小鼠, 大鼠, 山羊, Cow, Pig, 绵羊, 斑马鱼, 马, 兔, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) antibody
SOX2 适用: 人 ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 10F10 unconjugated

anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 89-119), (N-Term) antibody
SOX2 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB14026 unconjugated

anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (Middle Region) antibody
SOX2 适用: 人, 小鼠, 大鼠, 山羊, Cow, 绵羊, 斑马鱼, 马, 兔, 犬, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 89-119) antibody
SOX2 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-Fr: 1:100-1:1000. FACS: 1:50-1:200. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

说明

Positive Control: Human ESC , GL261 , A431 , NT2D1
Validation: Comparison, KO/KD, Orthogonal, Overexpression

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

储存液

Thimerosal (Merthiolate)

注意事项

This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Chiu, Wu, Kuo, Miao, Zheng, Chen, Lin, Chang, Wang, Chou: "Critical role of SOX2-IGF2 signaling in aggressiveness of bladder cancer." in: Scientific reports, Vol. 10, Issue 1, pp. 8261, (2020) (PubMed).

Lee, Sung, Kuo, Tsai, Wang, Pan, Chen, Wang, Wen, Chou: "Crosstalk between SOX2 and cytokine signaling in endometrial carcinoma." in: Scientific reports, Vol. 8, Issue 1, pp. 17550, (2019) (PubMed).

Seleit, Krämer, Riebesehl, Ambrosio, Stolper, Lischik, Dross, Centanin: "Neural stem cells induce the formation of their physical niche during organogenesis." in: eLife, Vol. 6, (2018) (PubMed).
抗原

SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

别名

SRY-box 2

背景

This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).

Cellular Localization: Nucleus

分子量

34 kDa

基因ID

6657

UniProt

P48431

途径

Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis