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CSTB 抗体

This anti-CSTB antibody is a 兔 多克隆 antibody detecting CSTB in IF, ICC 和 IHC (p). Suitable for 人.
产品编号 ABIN2855050
发货至: 中国

Quick Overview for CSTB 抗体 (ABIN2855050)

抗原

See all CSTB 抗体
CSTB (Cystatin B (Stefin B) (CSTB))

适用

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宿主

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克隆类型

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多克隆

标记

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This CSTB antibody is un-conjugated

应用范围

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Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 交叉反应

    人, 小鼠

    产品特性

    Rabbit Polyclonal antibody to Cystatin B (cystatin B (stefin B))
    Cystatin B antibody

    纯化方法

    Affinity purified by Protein A.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human Cystatin B. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    6.04 mg/mL

    缓冲液

    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    CSTB (Cystatin B (Stefin B) (CSTB))

    别名

    cystatin B

    背景

    The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1).

    Cellular Localization: Cytoplasm , Nucleus

    分子量

    11 kDa

    基因ID

    1476

    UniProt

    P04080

    途径

    Response to Water Deprivation
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