CSTB 抗体
Our Local Distributor
北京 101111
Quick Overview for CSTB 抗体 (ABIN2855050)
抗原
See all CSTB 抗体适用
宿主
克隆类型
标记
应用范围
-
-
交叉反应
- 人, 小鼠
-
产品特性
-
Rabbit Polyclonal antibody to Cystatin B (cystatin B (stefin B))
Cystatin B antibody -
纯化方法
- Affinity purified by Protein A.
-
免疫原
- Recombinant protein encompassing a sequence within the center region of human Cystatin B. The exact sequence is proprietary.
-
亚型
- IgG
-
-
-
-
应用备注
- ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 6.04 mg/mL
-
缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
-
储存液
- Thimerosal (Merthiolate)
-
注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
- CSTB (Cystatin B (Stefin B) (CSTB))
-
别名
- cystatin B
-
背景
-
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1).
Cellular Localization: Cytoplasm , Nucleus -
分子量
- 11 kDa
-
基因ID
- 1476
-
UniProt
- P04080
-
途径
- Response to Water Deprivation
抗原
-