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APOE 抗体 (N-Term)

Name: APOE 抗体 (N-Term)
Brand: antibodies-online
SKU: ABIN2855049
Availability: OutOfStock

This anti-APOE antibody is a 兔多克隆 antibody detecting APOE in WB, ICC, IHC (p) 和 IF. Suitable for 人. This Primary Antibody has been cited in 1 publication.

WB Image Whole cell extract (30 μg) was separated by 10% SDS-PAGE, and the membrane was blotted with Apolipoprotein E antibody , diluted at 1:1000. (APOE 抗体 (N-Term))

IHC-P Image Apolipoprotein E antibody detects Apolipoprotein E protein at secreted on human hepatoma by immunohistochemical analysis. (APOE 抗体 (N-Term))

IHC

WB Image Human tissue extract (30 μg) was separated by 10% SDS-PAGE, and the membrane was blotted with Apolipoprotein E antibody , diluted at 1:1000. (APOE 抗体 (N-Term))

3 images

(1 reference)

产品编号 ABIN2855049

发货至: 中国

Datasheet as PDF

Quick Overview for APOE 抗体 (N-Term) (ABIN2855049)

抗原

See all APOE 抗体

APOE (Apolipoprotein E (APOE))

适用

人

宿主

兔

克隆类型

多克隆

标记

This APOE antibody is un-conjugated

应用范围

Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Discover our top product APOE Primary Antibody

抗原表位
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N-Term

交叉反应

人

产品特性

Rabbit Polyclonal antibody to Apolipoprotein E (apolipoprotein E)
Apolipoprotein E antibody

纯化方法

Purified by antigen-affinity chromatography.

免疫原

Recombinant protein encompassing a sequence within the N-terminus region of human Apolipoprotein E. The exact sequence is proprietary.

亚型

IgG
anti-Apolipoprotein E (APOE) (AA 19-181) antibody
APOE 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Apolipoprotein E (APOE) (AA 19-168) antibody
APOE 适用: 大鼠 WB, IHC, IP, ICC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Apolipoprotein E (APOE) (AA 1-172) antibody
APOE 适用: 犬 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Apolipoprotein E (APOE) (AA 19-168) antibody
APOE 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C5 unconjugated

anti-Apolipoprotein E (APOE) (C-Term) antibody
APOE 适用: 人 WB, ELISA, IP, ICC, IHC (p), IF, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Apolipoprotein E (APOE) (AA 200-300) antibody
APOE 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Apolipoprotein E (APOE) antibody
APOE 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 1H4 unconjugated

anti-Apolipoprotein E (APOE) (AA 151-250) antibody
APOE 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Apolipoprotein E (APOE) (AA 14-167) antibody
APOE 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Apolipoprotein E (APOE) (AA 16-175) antibody
APOE 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

说明

Positive Control: A549 , human plasma

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

储存液

Thimerosal (Merthiolate)

注意事项

This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Ellis, Naugler, Nauglers, Parini, Mörk, Jorns, Zemack, Sandblom, Björkhem, Ericzon, Wilson, Strom, Grompe: "Mice with chimeric livers are an improved model for human lipoprotein metabolism." in: PLoS ONE, Vol. 8, Issue 11, pp. e78550, (2014) (PubMed).
抗原

APOE (Apolipoprotein E (APOE))

别名

apolipoprotein E

背景

Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.

Cellular Localization: Secreted

分子量

36 kDa

基因ID

348

UniProt

P02649

途径

Regulation of Cell Size, Lipid Metabolism