SAFB 抗体
Quick Overview for SAFB 抗体 (ABIN2855048)
抗原
See all SAFB 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
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Rabbit polyclonal antibody to Scaffold attachment factor B1 (scaffold attachment factor B)
Scaffold attachment factor B1 antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human SAFB. The exact sequence is proprietary.
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亚型
- IgG
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anti-Scaffold Attachment Factor B (SAFB) antibody
SAFB 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Scaffold Attachment Factor B (SAFB) (AA 1-200) antibodySAFB 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Scaffold Attachment Factor B (SAFB) (AA 111-200) antibodySAFB 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 5A11 unconjugated
anti-Scaffold Attachment Factor B (SAFB) (AA 111-201) antibodySAFB 适用: 人 WB, IHC, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 5A11 unconjugated
anti-Scaffold Attachment Factor B (SAFB) (AA 300-400) antibodySAFB 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Scaffold Attachment Factor B (SAFB) (C-Term) antibodySAFB 适用: 人, 小鼠, 兔 IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: 293T , A431 , HeLa , HepG2
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- SAFB (Scaffold Attachment Factor B (SAFB))
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别名
- scaffold attachment factor B
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背景
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This gene encodes a DNA-binding protein that has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. This encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes. It is involved in the regulation of the heat shock protein 27 transcription and also can act as an estrogen receptor corepressor. This gene is a candidate gene for breast tumorigenesis.
Cellular Localization: Nucleus -
分子量
- 103 kDa
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基因ID
- 6294
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UniProt
- Q15424
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway
抗原
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