HSP90AB1 抗体 (Internal Region)
Quick Overview for HSP90AB1 抗体 (Internal Region) (ABIN2855037)
抗原
See all HSP90AB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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交叉反应
- 猕猴, 牛
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交叉反应 (详细)
- Rhesus Monkey (100 %), Bovine (100 %)
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产品特性
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Rabbit Polyclonal antibody to HSP90 beta (heat shock protein 90 kDa alpha (cytosolic), class B member 1)
HSP90 beta antibody [N2C2], Internal -
纯化方法
- Affinity purified by Protein A.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human HSP90 beta. The exact sequence is proprietary.
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亚型
- IgG
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应用备注
- Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
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说明
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Positive Control: HeLaS3
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 5.43 mg/mL
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缓冲液
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "PGRMC2 is an intracellular haem chaperone critical for adipocyte function." in: Nature, Vol. 576, Issue 7785, pp. 138-142, (2020) (PubMed).
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: "PGRMC2 is an intracellular haem chaperone critical for adipocyte function." in: Nature, Vol. 576, Issue 7785, pp. 138-142, (2020) (PubMed).
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- HSP90AB1 (Heat Shock Protein 90kDa alpha (Cytosolic), Class B Member 1 (HSP90AB1))
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别名
- HSP90 beta
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背景
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HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. There are 2 major cytosolic HSP90 proteins, HSP90AA1 (MIM 140571), an inducible form, and HSP90AB1, a constitutive form. Other HSP90 proteins are found in endoplasmic reticulum (HSP90B1, MIM 191175) and mitochondria (TRAP1, MIM 606219) (Chen et al., 2005 [PubMed 16269234]).[supplied by OMIM]
Cellular Localization: Cytoplasm , Melanosome -
分子量
- 83 kDa
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基因ID
- 3326
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途径
- Regulation of Cell Size
抗原
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