Lactate Dehydrogenase A 抗体
(3 references)Quick Overview for Lactate Dehydrogenase A 抗体 (ABIN2855034)
抗原
See all Lactate Dehydrogenase A (LDHA) 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
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Rabbit Polyclonal antibody to Lactate Dehydrogenase (lactate dehydrogenase A)
LDHA antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human LDHA. The exact sequence is proprietary.
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亚型
- IgG
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anti-Lactate Dehydrogenase A (LDHA) (AA 1-332) antibody
LDHA 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lactate Dehydrogenase A (LDHA) antibodyLDHA 适用: 人 WB, IHC, IP, IHC (p) 宿主: 小鼠 Monoclonal 2D11 unconjugated
anti-Lactate Dehydrogenase A (LDHA) (AA 1-332) antibodyLDHA 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Lactate Dehydrogenase A (LDHA) (AA 1-332) antibodyLDHA 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Lactate Dehydrogenase A (LDHA) (Middle Region) antibodyLDHA 适用: 人, 小鼠, 大鼠, 兔, Cow, 马, 豚鼠, 犬, 山羊, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lactate Dehydrogenase A (LDHA) (AA 154-182) antibodyLDHA 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Lactate Dehydrogenase A (LDHA) (AA 204-232) antibodyLDHA 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Lactate Dehydrogenase A (LDHA) (AA 5-323) antibodyLDHA 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Lactate Dehydrogenase A (LDHA) (C-Term) antibodyLDHA 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lactate Dehydrogenase A (LDHA) antibodyLDHA 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: PC-12 , Rat2 , Neuro2A , C8D30 , NIH-3T3 , Raw264.7 , C2C12 , 293T , A431 , HeLa , HepG2
Validation: Orthogonal
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.33 mg/mL
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缓冲液
- 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "Targeting the Mevalonate Pathway Suppresses VHL-Deficient CC-RCC through an HIF-Dependent Mechanism." in: Molecular cancer therapeutics, Vol. 17, Issue 8, pp. 1781-1792, (2019) (PubMed).
: "Thiamine deficiency activates hypoxia inducible factor-1α to facilitate pro-apoptotic responses in mouse primary astrocytes." in: PLoS ONE, Vol. 12, Issue 10, pp. e0186707, (2017) (PubMed).
: "Continued 26S proteasome dysfunction in mouse brain cortical neurons impairs autophagy and the Keap1-Nrf2 oxidative defence pathway." in: Cell death & disease, Vol. 8, Issue 1, pp. e2531, (2017) (PubMed).
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: "Targeting the Mevalonate Pathway Suppresses VHL-Deficient CC-RCC through an HIF-Dependent Mechanism." in: Molecular cancer therapeutics, Vol. 17, Issue 8, pp. 1781-1792, (2019) (PubMed).
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- Lactate Dehydrogenase A (LDHA)
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别名
- lactate dehydrogenase A
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背景
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The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Multiple transcript variants encoding different isoforms have been found for this gene. The human genome contains several non-transcribed pseudogenes of this gene.
Cellular Localization: Cytoplasm -
分子量
- 37 kDa
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基因ID
- 3939
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UniProt
- P00338
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途径
- Warburg Effect
抗原
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