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ATRX 抗体 (C-Term)

This anti-ATRX antibody is a 兔 多克隆 antibody detecting ATRX in WB, IF, IHC (p), ICC 和 IP. Suitable for 人 和 小鼠.
产品编号 ABIN2855005
发货至: 中国

Quick Overview for ATRX 抗体 (C-Term) (ABIN2855005)

抗原

See all ATRX 抗体
ATRX (helicase 2, X-linked (ATRX))

适用

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  • 16
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人, 小鼠

宿主

  • 33
  • 21
  • 1

克隆类型

  • 30
  • 25
多克隆

标记

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  • 1
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This ATRX antibody is un-conjugated

应用范围

  • 29
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  • 2
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  • 1
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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunoprecipitation (IP)
  • 抗原表位

    • 7
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    • 3
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    C-Term

    交叉反应

    Chimpanzee

    交叉反应 (详细)

    Chimpanzee (100 %)

    产品特性

    Rabbit Polyclonal antibody to ATRX (alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae))
    ATRX antibody [C3], C-term

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the C-terminus region of human ATRX. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Immunoprecipitation 1:100-1:500* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Immunoprecipitation1:100-1:500* Western blot1:500-1:3000*

    说明

    Positive Control: 293T , A431 , HeLa , HepG2 , NIH3T3

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    2.67 mg/mL

    缓冲液

    1XPBS, 20 % Glycerol ( pH 7). 0.025 % ProClin 300 was added as a preservative.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    ATRX (helicase 2, X-linked (ATRX))

    别名

    ATRX

    背景

    The protein encoded by this gene contains an ATPase/helicase domain, and thus it belongs to the SWI/SNF family of chromatin remodeling proteins. The mutations of this gene are associated with an X-linked mental retardation (XLMR) syndrome most often accompanied by alpha-thalassemia (ATRX) syndrome. These mutations have been shown to cause diverse changes in the pattern of DNA methylation, which may provide a link between chromatin remodeling, DNA methylation, and gene expression in developmental processes. This protein is found to undergo cell cycle-dependent phosphorylation, which regulates its nuclear matrix and chromatin association, and suggests its involvement in the gene regulation at interphase and chromosomal segregation in mitosis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.

    分子量

    283 kDa

    基因ID

    546
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