DMPK 抗体 (Center)
Quick Overview for DMPK 抗体 (Center) (ABIN2854986)
抗原
See all DMPK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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产品特性
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Rabbit Polyclonal antibody to DMPK (dystrophia myotonica-protein kinase)
DMPK antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human DMPK. The exact sequence is proprietary.
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亚型
- IgG
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anti-Dystrophia Myotonica-Protein Kinase (DMPK) antibody
DMPK 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dystrophia Myotonica-Protein Kinase (DMPK) (AA 1-629) antibodyDMPK 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Dystrophia Myotonica-Protein Kinase (DMPK) (AA 303-420) antibodyDMPK 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 2F7 unconjugated
anti-Dystrophia Myotonica-Protein Kinase (DMPK) (AA 243-424) antibodyDMPK 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dystrophia Myotonica-Protein Kinase (DMPK) (N-Term) antibodyDMPK 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Dystrophia Myotonica-Protein Kinase (DMPK) (AA 323-372) antibodyDMPK 适用: 人, 小鼠, Cow, 犬, 豚鼠, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dystrophia Myotonica-Protein Kinase (DMPK) (N-Term) antibodyDMPK 适用: 人 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dystrophia Myotonica-Protein Kinase (DMPK) (AA 1-152) antibodyDMPK 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dystrophia Myotonica-Protein Kinase (DMPK) (Middle Region) antibodyDMPK 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dystrophia Myotonica-Protein Kinase (DMPK) (AA 1-629) antibodyDMPK 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
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说明
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Positive Control: U87-MG , SK-N-SH , SK-N-AS
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1XPBS, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- DMPK (Dystrophia Myotonica-Protein Kinase (DMPK))
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别名
- DMPK
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背景
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The protein encoded by this gene is a serine-threonine kinase that is closely related to other kinases that interact with members of the Rho family of small GTPases. Substrates for this enzyme include myogenin, the beta-subunit of the L-type calcium channels, and phospholemman. The 3' untranslated region of this gene contains 5-37 copies of a CTG trinucleotide repeat. Expansion of this unstable motif to 50-5,000 copies causes myotonic dystrophy type I, which increases in severity with increasing repeat element copy number. Repeat expansion is associated with condensation of local chromatin structure that disrupts the expression of genes in this region. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
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分子量
- 69 kDa
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基因ID
- 1760
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途径
- Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development
抗原
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