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DLD 抗体

This anti-DLD antibody is a 兔 多克隆 antibody detecting DLD in WB, IF, ICC 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2854985
发货至: 中国

Quick Overview for DLD 抗体 (ABIN2854985)

抗原

See all DLD 抗体
DLD (Dihydrolipoamide Dehydrogenase (DLD))

适用

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宿主

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克隆类型

  • 54
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多克隆

标记

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This DLD antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

KO Validated
  • 交叉反应

    人, 小鼠, 大鼠

    产品特性

    Rabbit Polyclonal antibody to DLD (dihydrolipoamide dehydrogenase)
    DLD antibody

    纯化方法

    Affinity purified by Protein A.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human DLD. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: Mouse brain , 293T , PC-12 , Rat2 , HeLa

    Validation: KO/KD

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Shin, Lee, You, Kim, Roh: "Dihydrolipoamide dehydrogenase regulates cystine deprivation-induced ferroptosis in head and neck cancer." in: Redox biology, Vol. 30, pp. 101418, (2020) (PubMed).

  • 抗原

    DLD (Dihydrolipoamide Dehydrogenase (DLD))

    别名

    dihydrolipoamide dehydrogenase

    背景

    This gene encodes the L protein of the mitochondrial glycine cleavage system. The L protein, also named dihydrolipoamide dehydrogenase, is also a component of the pyruvate dehydrogenase complex, the alpha-ketoglutarate dehydrogenase complex, and the branched-chain alpha-keto acide dehydrogenase complex. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency.

    Cellular Localization: Mitochondrion matrix

    分子量

    54 kDa

    基因ID

    1738

    UniProt

    P09622

    途径

    Ribonucleoside Biosynthetic Process, Cell RedoxHomeostasis
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