FLNB 抗体 (N-Term)
(1 reference)Quick Overview for FLNB 抗体 (N-Term) (ABIN2854971)
抗原
See all FLNB 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- N-Term
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交叉反应
- 人, 小鼠
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产品特性
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Rabbit Polyclonal antibody to Filamin B (filamin B, beta)
Filamin B antibody [N1], N-term -
纯化方法
- Affinity purified by Protein A.
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免疫原
- Recombinant protein encompassing a sequence within the N-terminus region of human Filamin B. The exact sequence is proprietary.
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亚型
- IgG
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anti-Filamin B, beta (FLNB) antibody
FLNB 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Filamin B, beta (FLNB) (AA 1686-1785) antibodyFLNB 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Filamin B, beta (FLNB) (AA 30-239) antibodyFLNB 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Filamin B, beta (FLNB) (AA 1-237) antibodyFLNB 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Filamin B, beta (FLNB) (AA 1551-1650) antibodyFLNB 适用: 人 WB, ELISA, ICC, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Filamin B, beta (FLNB) (AA 2061-2193) antibodyFLNB 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Filamin B, beta (FLNB) (AA 2061-2193) antibodyFLNB 适用: 人 WB, IHC, IP, IF/ICC 宿主: 兔 Polyclonal unconjugated
anti-Filamin B, beta (FLNB) (AA 163-196) antibodyFLNB 适用: 人 WB 宿主: 兔 Polyclonal RB54051 unconjugated
anti-Filamin B, beta (FLNB) (AA 288-322) antibodyFLNB 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB54052 unconjugated
anti-Filamin B, beta (FLNB) (AA 2503-2602) antibodyFLNB 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: U87-MG , NIH-3T3 , 293T , A431 , HeLa , HepG2
Validation: KO/KD
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 10 mg/mL
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缓冲液
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "Dense fibrillar collagen is a potent inducer of invadopodia via a specific signaling network." in: The Journal of cell biology, Vol. 208, Issue 3, pp. 331-50, (2015) (PubMed).
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: "Dense fibrillar collagen is a potent inducer of invadopodia via a specific signaling network." in: The Journal of cell biology, Vol. 208, Issue 3, pp. 331-50, (2015) (PubMed).
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- FLNB (Filamin B, beta (FLNB))
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别名
- filamin B
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背景
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This gene encodes a member of the filamin family. The encoded protein interacts with glycoprotein Ib alpha as part of the process to repair vascular injuries. The platelet glycoprotein Ib complex includes glycoprotein Ib alpha, and it binds the actin cytoskeleton. Mutations in this gene have been found in several conditions: atelosteogenesis type 1 and type 3, boomerang dysplasia, autosomal dominant Larsen syndrome, and spondylocarpotarsal synostosis syndrome. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
Cellular Localization: Isoform 1: Cytoplasm , cell cortex , Cytoplasm , cytoskeleton , myofibril , sarcomere , Z-disk , Isoform 2: Cytoplasm , Isoform 3: Cytoplasm , Isoform 6: Cytoplasm -
分子量
- 278 kDa
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基因ID
- 2317
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UniProt
- O75369
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途径
- Maintenance of Protein Location
抗原
-
