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FLNB 抗体 (N-Term)

This anti-FLNB antibody is a 兔 多克隆 antibody detecting FLNB in WB, IF, ICC 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2854971
发货至: 中国

Quick Overview for FLNB 抗体 (N-Term) (ABIN2854971)

抗原

See all FLNB 抗体
FLNB (Filamin B, beta (FLNB))

适用

  • 54
  • 9
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  • 2
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  • 1
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  • 1
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  • 1

宿主

  • 47
  • 6
  • 1

克隆类型

  • 48
  • 6
多克隆

标记

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  • 1
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This FLNB antibody is un-conjugated

应用范围

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  • 3
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Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

KO Validated
  • 抗原表位

    • 15
    • 4
    • 3
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    • 2
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    • 1
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    N-Term

    交叉反应

    人, 小鼠

    产品特性

    Rabbit Polyclonal antibody to Filamin B (filamin B, beta)
    Filamin B antibody [N1], N-term

    纯化方法

    Affinity purified by Protein A.

    免疫原

    Recombinant protein encompassing a sequence within the N-terminus region of human Filamin B. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: U87-MG , NIH-3T3 , 293T , A431 , HeLa , HepG2

    Validation: KO/KD

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    10 mg/mL

    缓冲液

    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Artym, Swatkoski, Matsumoto, Campbell, Petrie, Dimitriadis, Li, Mueller, Bugge, Gucek, Yamada: "Dense fibrillar collagen is a potent inducer of invadopodia via a specific signaling network." in: The Journal of cell biology, Vol. 208, Issue 3, pp. 331-50, (2015) (PubMed).

  • 抗原

    FLNB (Filamin B, beta (FLNB))

    别名

    filamin B

    背景

    This gene encodes a member of the filamin family. The encoded protein interacts with glycoprotein Ib alpha as part of the process to repair vascular injuries. The platelet glycoprotein Ib complex includes glycoprotein Ib alpha, and it binds the actin cytoskeleton. Mutations in this gene have been found in several conditions: atelosteogenesis type 1 and type 3, boomerang dysplasia, autosomal dominant Larsen syndrome, and spondylocarpotarsal synostosis syndrome. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.

    Cellular Localization: Isoform 1: Cytoplasm , cell cortex , Cytoplasm , cytoskeleton , myofibril , sarcomere , Z-disk , Isoform 2: Cytoplasm , Isoform 3: Cytoplasm , Isoform 6: Cytoplasm

    分子量

    278 kDa

    基因ID

    2317

    UniProt

    O75369

    途径

    Maintenance of Protein Location
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