GLA 抗体
Quick Overview for GLA 抗体 (ABIN2854962)
抗原
See all GLA 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
-
-
特异性
- Knockdown/Knockout validation was supported by customer review data.
-
交叉反应
- 人, 大鼠
-
产品特性
-
Rabbit Polyclonal antibody to Galactosidase alpha (galactosidase, alpha)
Galactosidase alpha antibody [N1C2] -
纯化方法
- Purified by antigen-affinity chromatography.
-
免疫原
- Recombinant protein encompassing a sequence within the center region of human Galactosidase alpha. The exact sequence is proprietary.
-
亚型
- IgG
-
-
-
-
应用备注
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
-
说明
-
Positive Control: HeLa , 293T , Rat lung
Validation: KO/KD
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.157 mg/mL
-
缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
-
- GLA (Galactosidase, alpha (GLA))
-
别名
- galactosidase alpha
-
背景
-
This gene encodes a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties.
Cellular Localization: Lysosome -
分子量
- 49 kDa
-
基因ID
- 2717
-
UniProt
- P06280
-
途径
- SARS-CoV-2 Protein Interactome
抗原
-