Prohibitin 抗体
(1 reference)Quick Overview for Prohibitin 抗体 (ABIN2854938)
抗原
See all Prohibitin (PHB) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
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Rabbit Polyclonal antibody to Prohibitin (prohibitin)
Prohibitin antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human Prohibitin. The exact sequence is proprietary.
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亚型
- IgG
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anti-Prohibitin (PHB) (AA 1-272) antibody
PHB 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3F4-2B2 unconjugated
anti-Prohibitin (PHB) antibodyPHB 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 5H7 unconjugated
anti-Prohibitin (PHB) (AA 177-272) antibodyPHB 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Prohibitin (PHB) (AA 167-261) antibodyPHB 适用: 人 WB, IHC, IF, StM 宿主: 小鼠 Monoclonal PHB-3194 unconjugated
anti-Prohibitin (PHB) (AA 73-272) antibodyPHB 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Prohibitin (PHB) (AA 167-261) antibodyPHB 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal PHB-3230 unconjugated
anti-Prohibitin (PHB) (AA 167-261) antibodyPHB 适用: 人 WB, IHC, IF, StM 宿主: 小鼠 Monoclonal PHB-3231 unconjugated
anti-Prohibitin (PHB) (AA 167-261) antibodyPHB 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal PHB-3193 unconjugated
anti-Prohibitin (PHB) (AA 167-261) antibodyPHB 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal PHB-1881 unconjugated
anti-Prohibitin (PHB) (AA 89-117) antibodyPHB 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB17513 unconjugated
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: NIH-3T3 , PC-12 , 293T
Validation: KO/KD, Orthogonal
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.34 mg/mL
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缓冲液
- 1XPBS pH 7, 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "A novel c-Kit/phospho-prohibitin axis enhances ovarian cancer stemness and chemoresistance via Notch3-PBX1 and β-catenin-ABCG2 signaling." in: Journal of biomedical science, Vol. 27, Issue 1, pp. 42, (2020) (PubMed).
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: "A novel c-Kit/phospho-prohibitin axis enhances ovarian cancer stemness and chemoresistance via Notch3-PBX1 and β-catenin-ABCG2 signaling." in: Journal of biomedical science, Vol. 27, Issue 1, pp. 42, (2020) (PubMed).
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- Prohibitin (PHB)
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别名
- prohibitin
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背景
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Prohibitin is an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA.
Cellular Localization: Mitochondrion inner membrane -
分子量
- 30 kDa
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基因ID
- 5245
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UniProt
- P35232
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
抗原
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